簡介：鹽酸異丙腎上腺素，Isoprenaline hydrochloride是一種非選擇性的β-腎上腺素能受體激動劑，具有有效的外周血管擴張劑，支氣管擴張劑和心臟刺激活性。
鹽酸異丙腎上腺素物理化學性質(zhì)：
|
密度 |
1.324 g/cm3 |
|
沸點 |
417.5oC at 760 mmHg |
|
熔點 |
165-175 °C (dec.)(lit.) |
|
分子式 |
C11H18ClNO3 |
|
分子量 |
247.719 |
|
閃點 |
179.7oC |
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精確質(zhì)量 |
247.097519 |
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PSA |
72.72 |
|
LogP |
2.3221 |
|
外觀性狀 |
白色結(jié)晶粉末 |
|
儲存條件 |
本品應(yīng)密封于陰涼避光處保存。 |
|
穩(wěn)定性 |
Stable, but may be air and light sensitive. Incompatible with strong oxidizing agents. |
|
水溶解性 |
Soluble |
鹽酸異丙腎上腺素詳細介紹：
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中文名稱： |
鹽酸異丙腎上腺素 |
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中文別名： |
鹽酸異丙腎上腺素;異丙腎上腺素鹽酸鹽;4-[(2-異丙氨基-1-羥基)乙基]-1,2-苯二酚鹽酸鹽;鹽酸異丙腎上腺素原藥;異丙腎上腺素;異丙腎上腺素鹽酸鹽 USP標準品 |
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英文名稱： |
Isoproterenol hydrochloride |
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英文別名： |
isoprenaline hydrochloride;Isoproterenol, HCl;2-benzenediol,4-(1-hydroxy-2-((1-methylethyl)amino)ethyl)-hydrochloride;3,4-dihydroxy-alpha-((isopropylamino)methyl)-benzylalcohohydrochloride;alpha-(isopropylaminomethyl)-3,4-dihydroxybenzylalcoholhydrochloride;euspiran;isadrine;isoprenalinechloride;isopropylnorepinephrine-hydrochloride;isoproterenolmonohydrochloride;Isoprenaline HCl;Isolated soy protein;Isoproterenol Hydrochloride;Isoproterenol (hydrochloride);[3H]-Isoproterenol hydrochloride;Isomenyl;isoprenaline;Isoprenaline (hydrochloride);Isovon;isuprel;Mistarel;proternol;Saventrine IV;Suscardia;(±)-Isoproterenol hydrochloride;1-(3′,4′-Dihydroxyphenyl)-2-isopropylaminoethanol hydrochloride;N-Isopropyl-DL-noradrenaline hydrochloride;3,4-Dihydroxy-alpha-((isopropylamino)methyl)-benzyl alcohol hydrochloride;4-(1-Hydroxy-2-((methylethyl)amino)ethyl)-1,2-benzenediol hydrochloride;Aludrine hydrochloride;Isoproterenol HCl;Aerolone;Aerotrol;Izadrin;Vapo-Iso;DL-Isoprenaline hydrochloride;DL-Isoproterenol hydrochloride;Isuprel hydrochloride;Asthpul;Norisodrine hydrochloride;Isopropylarterenol hydrochloride;dl-Isadrine hydrochloride;(+-)-Isoproterenol hydrochloride;Norisodrine Aerotrol;Isoprenaline chloride;Isoproterenol monohydrochloride;(+-)-Isoprenaline hydrochl |
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CAS號： |
51-30-9 |
|
分子式： |
C11H18CLNO3 |
|
分子量： |
247.72 |
|
詳細描述 |
博飛美科商城提供的[Sigma-Aldrich]Isoprenaline Hydrochloride為博飛美科出品的其它生化試劑,產(chǎn)品穩(wěn)定,定制速度快,極大地方便了廣大科研客戶的使用需求。產(chǎn)品包裝為25G，安全運輸。 屬性： mp：165-175 °C (dec.) (lit.) SMILES string：Cl.CC(C)NCC(O)c1ccc(O)c(O)c1 InChI：1S/C11H17NO3.ClH/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8;/h3-5,7,11-15H,6H2,1-2H3;1H InChI key：IROWCYIEJAOFOW-UHFFFAOYSA-N 包裝： 5, 25, 100 g in poly bottle 生化/生理作用： β-腎上腺素受體激活劑，增加胞質(zhì)cAMP。 查詢關(guān)鍵詞:“51-30-9，鹽酸異丙腎上腺素，Isoprenaline Hydrochloride，Sigma-Aldrich，上?，F(xiàn)貨，以Sigma官網(wǎng)為準”。 |
鹽酸異丙腎上腺素參考文獻：
[1]. Degerman E, et al. Evidence that insulin and isoprenaline activate the cGMP-inhibited low-Km cAMP phosphodiesterase in rat fat cells by phosphorylation. Proc Natl Acad Sci U S A. 1990 Jan;87(2):533-7
[2]. Vannucci SJ, et al. Cell surface accessibility of GLUT4 glucose transporters in insulin-stimulated rat adipose cells. Modulation by isoprenaline and adenosine. Biochem J. 1992 Nov 15;288 (Pt 1):325-30.
[3]. Delpy E, et al. Effects of cyclic GMP elevation on isoprenaline-induced increase in cyclic AMP and relaxation in rat aortic smooth muscle: role of phosphodiesterase 3. Br J Pharmacol. 1996 Oct;119(3):471-8.
[4]. Muller FU, et al. Isoprenaline stimulates gene transcription of the inhibitory G protein alpha-subunit Gi alpha-2 in rat heart. Circ Res. 1993 Mar;72(3):696-700.
[5]. Lei M, et al. Modulation of delayed rectifier potassium current, iK, by isoprenaline in rabbit isolated pacemaker cells. Exp Physiol. 2000 Jan;85(1):27-35.
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